Dyslexia and dyscalculia are genetic predispositions that run in families. Genetic processes during the development of the brain shape how the sensory perceptions are formed. This is why a dyslexic person takes in letters and numbers differently from the very beginning. Research points to chromosomes 15 and 6, and an estimated 15 to 20 percent of people are affected.
Sources: Albert M. Galaburda et al., Harvard Medical School, From genes to behavior in developmental dyslexia, Nature Neuroscience 9 (10), 2006, pages 1213 to 1217. International Dyslexia Association, Dyslexia Basics.
These different sensory perceptions are not only a hurdle. They can be a huge advantage, which is why dyslexia is often described as a gift. Because dyslexic people process information in their own way, many of them are highly talented in the arts, in music, in science, in athletics, and in any field that rewards thinking in pictures, spotting patterns, and finding solutions that others miss.
What their perception is not built for are the abstract basic academic skills of reading, spelling, writing, and/or calculating. That is where targeted training comes in, so that the talent is not held back by the symbols.